DeCS Server - List Exact Term

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DeCS

Descriptor Inglés:

STAT Transcription Factors

Descriptor Español:

Factores de Transcripción STAT

Descriptor Portugués:

Fatores de Transcrição STAT

Sinónimos Inglés:

STAT (Signal Transducers and Activators of Transcription) Proteins
Transcription Factors, STAT

Categoría:

Definición Inglés:

A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.

Nota de Indización Inglés:

general; prefer specifics

Nota Histórica Inglés:

2006

Calificadores Permitidos Inglés:

Número del Registro:

50795

Identificador Único:

D050791

Similar:

DeCS